Cargando…
Analysis of endogenous and exogenous tumor upregulated promoter expression in canine tumors
Gene therapy is a promising treatment option for cancer. However, its utility may be limited due to expression in off-target cells. Cancer-specific promoters such as telomerase reverse transcriptase (TERT), survivin, and chemokine receptor 4 (CXCR4) have enhanced activity in a variety of human and m...
Autores principales: | Sajib, Abdul Mohin, Sandey, Maninder, Morici, Samantha, Schuler, Bradley, Agarwal, Payal, Smith, Bruce F. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7652315/ https://www.ncbi.nlm.nih.gov/pubmed/33166332 http://dx.doi.org/10.1371/journal.pone.0240807 |
Ejemplares similares
-
Cell-Surface Integrins and CAR Are Both Essential for Adenovirus Type 5 Transduction of Canine Cells of Lymphocytic Origin
por: Agarwal, Payal, et al.
Publicado: (2017) -
Evaluation of tumor immunity after administration of conditionally replicative adenoviral vector in canine osteosarcoma patients
por: Agarwal, Payal, et al.
Publicado: (2021) -
Characterization of Canine Adenovirus Type 2 Virus Infection Pattern in Canine and Human Cell Lines
por: Hogans, Madison D., et al.
Publicado: (2022) -
Single-Nuclei Multiome (ATAC + Gene Expression) Sequencing of a Primary Canine Osteosarcoma Elucidates Intra-Tumoral Heterogeneity and Characterizes the Tumor Microenvironment
por: Nance, Rebecca L., et al.
Publicado: (2023) -
Development of OX40 agonists for canine cancer immunotherapy
por: Ruiz, Damien, et al.
Publicado: (2022)