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Exploring the Complexity of Protein-Level Dosage Compensation that Fine-Tunes Stoichiometry of Multiprotein Complexes

Proper control of gene expression levels upon various perturbations is a fundamental aspect of cellular robustness. Protein-level dosage compensation is one mechanism buffering perturbations to stoichiometry of multiprotein complexes through accelerated proteolysis of unassembled subunits. Although...

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Detalles Bibliográficos
Autores principales: Ishikawa, Koji, Ishihara, Akari, Moriya, Hisao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7652333/
https://www.ncbi.nlm.nih.gov/pubmed/33112847
http://dx.doi.org/10.1371/journal.pgen.1009091