A multivariate, quantitative assay that disentangles key kinetic parameters of primary human T cell function in vitro

Cell therapy is poised to play a larger role in medicine, most notably for immuno-oncology. Despite the recent success of CAR-T therapeutics in the treatment of blood tumors and the rapid progress toward improved versions of both CAR- and TCR-Ts, important analytical aspects of preclinical developme...

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Detalles Bibliográficos
Autores principales: Huang, Grace L., Nampe, Daniel P., Yi, Jason, Gabrelow, Grant B., Negri, Kathleen R., Kamb, Alexander, Xu, Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7652339/
https://www.ncbi.nlm.nih.gov/pubmed/33166305
http://dx.doi.org/10.1371/journal.pone.0241421

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7652339/
https://www.ncbi.nlm.nih.gov/pubmed/33166305
http://dx.doi.org/10.1371/journal.pone.0241421

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