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A multivariate, quantitative assay that disentangles key kinetic parameters of primary human T cell function in vitro
Cell therapy is poised to play a larger role in medicine, most notably for immuno-oncology. Despite the recent success of CAR-T therapeutics in the treatment of blood tumors and the rapid progress toward improved versions of both CAR- and TCR-Ts, important analytical aspects of preclinical developme...
Autores principales: | Huang, Grace L., Nampe, Daniel P., Yi, Jason, Gabrelow, Grant B., Negri, Kathleen R., Kamb, Alexander, Xu, Han |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7652339/ https://www.ncbi.nlm.nih.gov/pubmed/33166305 http://dx.doi.org/10.1371/journal.pone.0241421 |
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