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Graph-theoretical formulation of the generalized epitope-based vaccine design problem

Epitope-based vaccines have revolutionized vaccine research in the last decades. Due to their complex nature, bioinformatics plays a pivotal role in their development. However, existing algorithms address only specific parts of the design process or are unable to provide formal guarantees on the qua...

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Detalles Bibliográficos
Autores principales: Dorigatti, Emilio, Schubert, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7652351/
https://www.ncbi.nlm.nih.gov/pubmed/33095790
http://dx.doi.org/10.1371/journal.pcbi.1008237