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Evaluation of in vitro and in vivo Efficacy of a Novel Amphotericin B-Loaded Nanostructured Lipid Carrier in the Treatment of Leishmania braziliensis Infection

BACKGROUND: Leishmaniasis is a neglected disease, and the current therapeutic arsenal for its treatment is seriously limited by high cost and toxicity. Nanostructured lipid carriers (NLCs) represent a promising approach due to high drug loading capacity, controlled drug release profiles and superior...

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Detalles Bibliográficos
Autores principales: Rebouças-Silva, Jéssica, Tadini, Maraine Catarina, Devequi-Nunes, Danielle, Mansur, Ana Luíza, S Silveira-Mattos, Paulo, I de Oliveira, Camila, R Formiga, Fábio, Berretta, Andresa A, Marquele-Oliveira, Franciane, Borges, Valéria M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7652360/
https://www.ncbi.nlm.nih.gov/pubmed/33177824
http://dx.doi.org/10.2147/IJN.S262642