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Aberrant autophagosome formation occurs upon small molecule inhibition of ULK1 kinase activity
Autophagy is a crucial homeostatic mechanism that mediates the degradation of damaged or excess intracellular components. Such components are engulfed and sequestered into double membrane autophagosomes, which deliver their contents to lysosomes for degradation. Autophagy plays a role in numerous hu...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Life Science Alliance LLC
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7652397/ https://www.ncbi.nlm.nih.gov/pubmed/33109685 http://dx.doi.org/10.26508/lsa.202000815 |