Balancing selection and high genetic diversity of Plasmodium vivax circumsporozoite central region in parasites from Brazilian Amazon and Rio de Janeiro Atlantic Forest

Circumsporozoite protein (CSP) is the primary pre-erythrocytic vaccine target in Plasmodium species. Knowledge about their genetic diversity can help predict vaccine efficacy and the spread of novel parasite variants. Thus, we investigated pvcsp gene polymorphisms in 219 isolates (136 from Brazilian...

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Detalles Bibliográficos
Autores principales: Almeida-de-Oliveira, Natália Ketrin, de Abreu-Fernandes, Rebecca, Lima-Cury, Lidiane, de Lavigne, Aline Rosa, de Pina-Costa, Anielle, Perce-da-Silva, Daiana de Souza, Catanho, Marcos, Rossi, Atila Duque, Brasil, Patrícia, Tadeu Daniel-Ribeiro, Cláudio, Ferreira-da-Cruz, Maria de Fátima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7652573/
https://www.ncbi.nlm.nih.gov/pubmed/33166298
http://dx.doi.org/10.1371/journal.pone.0241426

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7652573/
https://www.ncbi.nlm.nih.gov/pubmed/33166298
http://dx.doi.org/10.1371/journal.pone.0241426

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