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Identification of Differential Gene Expression Pattern in Lens Epithelial Cells Derived from Cataractous and Noncataractous Lenses of Shumiya Cataract Rat

The Shumiya cataract rat (SCR) is a model for hereditary cataract. Two-thirds of these rats develop lens opacity within 10-11 weeks. Onset of cataract is attributed to the synergetic effect of lanosterol synthase (Lss) and farnesyl-diphosphate farnesyltransferase 1 (Fdft1) mutant alleles that lead t...

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Detalles Bibliográficos
Autores principales: Ishida, Hidetoshi, Shibata, Teppei, Nakamura, Yuka, Ishigaki, Yasuhito, Singh, Dhirendra P., Sasaki, Hiroshi, Kubo, Eri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7652612/
https://www.ncbi.nlm.nih.gov/pubmed/33204712
http://dx.doi.org/10.1155/2020/7319590