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Inhibition of interleukin‐1β signalling promotes atherosclerotic lesion remodelling in mice with inflammatory arthritis
OBJECTIVES: Rheumatoid arthritis (RA), an inflammatory joint disorder, independently increases the risk of cardiovascular disease (CVD). IL‐1β contributes to both RA and CVD. We hypothesised that inhibiting IL‐1 signalling with the IL‐1R antagonist, anakinra, would dampen inflammation and promote re...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7652637/ https://www.ncbi.nlm.nih.gov/pubmed/33204425 http://dx.doi.org/10.1002/cti2.1206 |