Inhibition of interleukin‐1β signalling promotes atherosclerotic lesion remodelling in mice with inflammatory arthritis

OBJECTIVES: Rheumatoid arthritis (RA), an inflammatory joint disorder, independently increases the risk of cardiovascular disease (CVD). IL‐1β contributes to both RA and CVD. We hypothesised that inhibiting IL‐1 signalling with the IL‐1R antagonist, anakinra, would dampen inflammation and promote re...

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Detalles Bibliográficos
Autores principales: Dragoljevic, Dragana, Lee, Man Kit Sam, Louis, Cynthia, Shihata, Waled, Kraakman, Michael J, Hansen, Jacinta, Masters, Seth L, Hanaoka, Beatriz Y, Nagareddy, Prabhakara R, Lancaster, Graeme I, Wicks, Ian P, Murphy, Andrew J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7652637/
https://www.ncbi.nlm.nih.gov/pubmed/33204425
http://dx.doi.org/10.1002/cti2.1206

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