Wwox Deficiency Causes Downregulation of Prosurvival ERK Signaling and Abnormal Homeostatic Responses in Mouse Skin

Deficiency of tumor suppressor WW domain-containing oxidoreductase (WWOX) in humans and animals leads to growth retardation and premature death during postnatal developmental stages. Skin integrity is essential for organism survival due to its protection against dehydration and hypothermia. Our prev...

Descripción completa

Detalles Bibliográficos
Autores principales: Chou, Ying-Tsen, Lai, Feng-Jie, Chang, Nan-Shan, Hsu, Li-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7652735/
https://www.ncbi.nlm.nih.gov/pubmed/33195192
http://dx.doi.org/10.3389/fcell.2020.558432

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7652735/
https://www.ncbi.nlm.nih.gov/pubmed/33195192
http://dx.doi.org/10.3389/fcell.2020.558432

Ejemplares similares