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Autocrine effects of PCSK9 on cardiomyocytes

Proprotein convertase subtilisin kexin type 9 (PCSK9) is in the focus of cardiovascular research due to its role in hepatic low density lipoprotein (LDL) clearance. However, extrahepatic expression of PCSK9 such as in cardiomyocytes and its regulation by oxidized LDL (oxLDL) put notion on extrahepat...

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Detalles Bibliográficos
Autores principales: Wolf, Annemarie, Kutsche, Hanna Sarah, Schreckenberg, Rolf, Weber, Martin, Li, Ling, Rohrbach, Susanne, Schulz, Rainer, Schlüter, Klaus-Dieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7652747/
https://www.ncbi.nlm.nih.gov/pubmed/33169229
http://dx.doi.org/10.1007/s00395-020-00824-w