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Structure-Based Design of Acetolactate Synthase From Bacillus licheniformis Improved Protein Stability Under Acidic Conditions

Catabolic acetolactate synthase (cALS) plays a crucial role in the quality of liquor because of its ability to catalyze the synthesis of the endogenous precursor product α-acetolactate of the aromatic compound tetramethylpyrazine (TTMP) and acetoin. However, the vulnerability of cALS to acidic condi...

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Detalles Bibliográficos
Autores principales: Zhao, Ting, Li, Yuan, Yuan, Siqi, Ye, Yang, Peng, Zhifu, Zhou, Rongqing, Liu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7652814/
https://www.ncbi.nlm.nih.gov/pubmed/33193222
http://dx.doi.org/10.3389/fmicb.2020.582909