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Structure-Based Design of Acetolactate Synthase From Bacillus licheniformis Improved Protein Stability Under Acidic Conditions
Catabolic acetolactate synthase (cALS) plays a crucial role in the quality of liquor because of its ability to catalyze the synthesis of the endogenous precursor product α-acetolactate of the aromatic compound tetramethylpyrazine (TTMP) and acetoin. However, the vulnerability of cALS to acidic condi...
Autores principales: | Zhao, Ting, Li, Yuan, Yuan, Siqi, Ye, Yang, Peng, Zhifu, Zhou, Rongqing, Liu, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7652814/ https://www.ncbi.nlm.nih.gov/pubmed/33193222 http://dx.doi.org/10.3389/fmicb.2020.582909 |
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