Human endogenous retroviruses form a reservoir of T cell targets in hematological cancers

Human endogenous retroviruses (HERV) form a substantial part of the human genome, but mostly remain transcriptionally silent under strict epigenetic regulation, yet can potentially be reactivated by malignant transformation or epigenetic therapies. Here, we evaluate the potential for T cell recognit...

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Detalles Bibliográficos
Autores principales: Saini, Sunil Kumar, Ørskov, Andreas Due, Bjerregaard, Anne-Mette, Unnikrishnan, Ashwin, Holmberg-Thydén, Staffan, Borch, Annie, Jensen, Kathrine Valentini, Anande, Govardhan, Bentzen, Amalie Kai, Marquard, Andrea Marion, Tamhane, Tripti, Treppendahl, Marianne Bach, Gang, Anne Ortved, Dufva, Inge Høgh, Szallasi, Zoltan, Ternette, Nicola, Pedersen, Anders Gorm, Eklund, Aron Charles, Pimanda, John, Grønbæk, Kirsten, Hadrup, Sine Reker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7653045/
https://www.ncbi.nlm.nih.gov/pubmed/33168830
http://dx.doi.org/10.1038/s41467-020-19464-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7653045/
https://www.ncbi.nlm.nih.gov/pubmed/33168830
http://dx.doi.org/10.1038/s41467-020-19464-8

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