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Differential association of CD68(+) and CD163(+) macrophages with macrophage enzymes, whole tumour gene expression and overall survival in advanced melanoma

BACKGROUND: The density and phenotype of tumour-associated macrophages have been linked with prognosis in a range of solid tumours. While there is strong preclinical evidence that tumour-associated macrophages promote aspects of tumour progression, it can be challenging to infer clinical activity fr...

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Detalles Bibliográficos
Autores principales: Tremble, Liam Friel, McCabe, Mark, Walker, Sidney P., McCarthy, Siobhán, Tynan, Réiltín F., Beecher, Suzanne, Werner, Réiltín, Clover, A. James P., Power, X. Derek G., Forde, Patrick F., Heffron, Cynthia C. B. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7653046/
https://www.ncbi.nlm.nih.gov/pubmed/32843682
http://dx.doi.org/10.1038/s41416-020-01037-7