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Differential association of CD68(+) and CD163(+) macrophages with macrophage enzymes, whole tumour gene expression and overall survival in advanced melanoma
BACKGROUND: The density and phenotype of tumour-associated macrophages have been linked with prognosis in a range of solid tumours. While there is strong preclinical evidence that tumour-associated macrophages promote aspects of tumour progression, it can be challenging to infer clinical activity fr...
Autores principales: | Tremble, Liam Friel, McCabe, Mark, Walker, Sidney P., McCarthy, Siobhán, Tynan, Réiltín F., Beecher, Suzanne, Werner, Réiltín, Clover, A. James P., Power, X. Derek G., Forde, Patrick F., Heffron, Cynthia C. B. B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7653046/ https://www.ncbi.nlm.nih.gov/pubmed/32843682 http://dx.doi.org/10.1038/s41416-020-01037-7 |
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