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SRC and PIM1 as potential co-targets to overcome resistance in MET deregulated non-small cell lung cancer

BACKGROUND: The role of MET alterations in non-small cell lung cancer (NSCLC) is increasing and several targeted agents are under evaluation. MET exon 14 skipping mutations and MET amplifications are associated with potential sensitivity to MET inhibition, though resistance mechanisms are emerging....

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Detalles Bibliográficos
Autores principales: Attili, Ilaria, Bonanno, Laura, Karachaliou, Niki, Bracht, Jillian Wilhelmina Paulina, Berenguer, Jordi, Codony-Servat, Carles, Codony-Servat, Jordi, Aldeguer, Erika, Gimenez-Capitan, Ana, Dal Maso, Alessandro, Fassan, Matteo, Chaib, Imane, Molina-Vila, Miguel Angel, Passaro, Antonio, de Marinis, Filippo, Pasello, Giulia, Guarneri, Valentina, Conte, Pier Franco, Rosell, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7653128/
https://www.ncbi.nlm.nih.gov/pubmed/33209603
http://dx.doi.org/10.21037/tlcr-20-681