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SRC and PIM1 as potential co-targets to overcome resistance in MET deregulated non-small cell lung cancer
BACKGROUND: The role of MET alterations in non-small cell lung cancer (NSCLC) is increasing and several targeted agents are under evaluation. MET exon 14 skipping mutations and MET amplifications are associated with potential sensitivity to MET inhibition, though resistance mechanisms are emerging....
Autores principales: | , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7653128/ https://www.ncbi.nlm.nih.gov/pubmed/33209603 http://dx.doi.org/10.21037/tlcr-20-681 |