Cargando…
SRC and PIM1 as potential co-targets to overcome resistance in MET deregulated non-small cell lung cancer
BACKGROUND: The role of MET alterations in non-small cell lung cancer (NSCLC) is increasing and several targeted agents are under evaluation. MET exon 14 skipping mutations and MET amplifications are associated with potential sensitivity to MET inhibition, though resistance mechanisms are emerging....
Autores principales: | Attili, Ilaria, Bonanno, Laura, Karachaliou, Niki, Bracht, Jillian Wilhelmina Paulina, Berenguer, Jordi, Codony-Servat, Carles, Codony-Servat, Jordi, Aldeguer, Erika, Gimenez-Capitan, Ana, Dal Maso, Alessandro, Fassan, Matteo, Chaib, Imane, Molina-Vila, Miguel Angel, Passaro, Antonio, de Marinis, Filippo, Pasello, Giulia, Guarneri, Valentina, Conte, Pier Franco, Rosell, Rafael |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7653128/ https://www.ncbi.nlm.nih.gov/pubmed/33209603 http://dx.doi.org/10.21037/tlcr-20-681 |
Ejemplares similares
-
STAT3 as a potential immunotherapy biomarker in oncogene-addicted non-small cell lung cancer
por: Attili, Ilaria, et al.
Publicado: (2018) -
Osimertinib and pterostilbene in EGFR-mutation-positive non-small cell lung cancer (NSCLC)
por: Bracht, Jillian Wilhelmina Paulina, et al.
Publicado: (2019) -
Integrin-linked kinase (ILK) and src homology 2 domain-containing phosphatase 2 (SHP2): Novel targets in EGFR-mutation positive non-small cell lung cancer (NSCLC)
por: Karachaliou, Niki, et al.
Publicado: (2018) -
Activation of signal transducer and activator of transcription 3 (STAT3) signaling in EGFR mutant non-small-cell lung cancer (NSCLC)
por: Codony-Servat, Carles, et al.
Publicado: (2017) -
Targeting PKCι-PAK1 signaling pathways in EGFR and KRAS mutant adenocarcinoma and lung squamous cell carcinoma
por: Ito, Masaoki, et al.
Publicado: (2019)