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PENGUINN: Precise Exploration of Nuclear G-Quadruplexes Using Interpretable Neural Networks

G-quadruplexes (G4s) are a class of stable structural nucleic acid secondary structures that are known to play a role in a wide spectrum of genomic functions, such as DNA replication and transcription. The classical understanding of G4 structure points to four variable length guanine strands joined...

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Detalles Bibliográficos
Autores principales: Klimentova, Eva, Polacek, Jakub, Simecek, Petr, Alexiou, Panagiotis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7653191/
https://www.ncbi.nlm.nih.gov/pubmed/33193663
http://dx.doi.org/10.3389/fgene.2020.568546