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PENGUINN: Precise Exploration of Nuclear G-Quadruplexes Using Interpretable Neural Networks
G-quadruplexes (G4s) are a class of stable structural nucleic acid secondary structures that are known to play a role in a wide spectrum of genomic functions, such as DNA replication and transcription. The classical understanding of G4 structure points to four variable length guanine strands joined...
Autores principales: | Klimentova, Eva, Polacek, Jakub, Simecek, Petr, Alexiou, Panagiotis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7653191/ https://www.ncbi.nlm.nih.gov/pubmed/33193663 http://dx.doi.org/10.3389/fgene.2020.568546 |
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