HIF‐1α ameliorates tubular injury in diabetic nephropathy via HO‐1–mediated control of mitochondrial dynamics

OBJECTIVES: In diabetic nephropathy (DN), hypoxia‐inducible factor‐1α (HIF‐1α) activation in tubular cells plays an important protective role against kidney injury. The effects may occur via the target genes of HIF‐1α, such as haem oxygenase‐1 (HO‐1), but the exact mechanisms are incompletely unders...

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Detalles Bibliográficos
Autores principales: Jiang, Na, Zhao, Hao, Han, Yachun, Li, Li, Xiong, Shan, Zeng, Lingfeng, Xiao, Ying, Wei, Ling, Xiong, Xiaofen, Gao, Peng, Yang, Ming, Liu, Yu, Sun, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7653251/
https://www.ncbi.nlm.nih.gov/pubmed/32975326
http://dx.doi.org/10.1111/cpr.12909

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7653251/
https://www.ncbi.nlm.nih.gov/pubmed/32975326
http://dx.doi.org/10.1111/cpr.12909

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