Cargando…

HIF‐1α ameliorates tubular injury in diabetic nephropathy via HO‐1–mediated control of mitochondrial dynamics

OBJECTIVES: In diabetic nephropathy (DN), hypoxia‐inducible factor‐1α (HIF‐1α) activation in tubular cells plays an important protective role against kidney injury. The effects may occur via the target genes of HIF‐1α, such as haem oxygenase‐1 (HO‐1), but the exact mechanisms are incompletely unders...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jiang, Na, Zhao, Hao, Han, Yachun, Li, Li, Xiong, Shan, Zeng, Lingfeng, Xiao, Ying, Wei, Ling, Xiong, Xiaofen, Gao, Peng, Yang, Ming, Liu, Yu, Sun, Lin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7653251/ https://www.ncbi.nlm.nih.gov/pubmed/32975326 http://dx.doi.org/10.1111/cpr.12909

Ejemplares similares

Lipophagy deficiency exacerbates ectopic lipid accumulation and tubular cells injury in diabetic nephropathy
por: Han, Yachun, et al.
Publicado: (2021)

MicroRNA-122-5p ameliorates tubular injury in diabetic nephropathy via FIH-1/HIF-1α pathway
por: Cheng, Li, et al.
Publicado: (2022)

AdipoRon Protects against Tubular Injury in Diabetic Nephropathy by Inhibiting Endoplasmic Reticulum Stress
por: Xiong, Shan, et al.
Publicado: (2020)

Reactive oxygen species promote tubular injury in diabetic nephropathy: The role of the mitochondrial ros-txnip-nlrp3 biological axis
por: Han, Yachun, et al.
Publicado: (2018)

Ferroptosis Enhanced Diabetic Renal Tubular Injury via HIF-1α/HO-1 Pathway in db/db Mice
por: Feng, Xiaomeng, et al.
Publicado: (2021)

Rap1 Ameliorates Renal Tubular Injury in Diabetic Nephropathy
por: Xiao, Li, et al.
Publicado: (2014)

DsbA-L Ameliorates Renal Injury Through the AMPK/NLRP3 Inflammasome Signaling Pathway in Diabetic Nephropathy
por: Yang, Ming, et al.
Publicado: (2021)

Edaravone Improves Septic Cardiac Function by Inducing an HIF-1α/HO-1 Pathway
por: He, Chao, et al.
Publicado: (2018)

The role of HIF-1α/HO-1 pathway in hippocampal neuronal ferroptosis in epilepsy
por: Liang, Zhen, et al.
Publicado: (2023)

Panax notoginseng saponins ameliorate cisplatin‐induced mitochondrial injury via the HIF‐1α/mitochondria/ROS pathway
por: Li, Qingqing, et al.
Publicado: (2019)

Dexmedetomidine ameliorates endotoxin-induced acute lung injury in vivo and in vitro by preserving mitochondrial dynamic equilibrium through the HIF-1a/HO-1 signaling pathway
por: Shi, Jia, et al.
Publicado: (2021)

Probucol ameliorates renal injury in diabetic nephropathy by inhibiting the expression of the redox enzyme p66Shc
por: Yang, Shikun, et al.
Publicado: (2017)

Carbohydrate restriction ameliorates nephropathy by reducing oxidative stress and upregulating HIF-1α levels in type-1 diabetic rats
por: Krishan, Pawan, et al.
Publicado: (2017)

Sirtuin4 alleviates severe acute pancreatitis by regulating HIF-1α/HO-1 mediated ferroptosis
por: Liu, Yanna, et al.
Publicado: (2023)

Heme oxygenase-1(HO-1) regulates Golgi stress and attenuates endotoxin-induced acute lung injury through hypoxia inducible factor-1α (HIF-1α)/HO-1 signaling pathway
por: Li, Xiangyun, et al.
Publicado: (2021)

SOCS5 knockdown suppresses metastasis of hepatocellular carcinoma by ameliorating HIF-1α-dependent mitochondrial damage
por: Luo, Dingan, et al.
Publicado: (2022)

Inhibition of HIF-1α-AQP4 axis ameliorates brain edema and neurological functional deficits in a rat controlled cortical injury (CCI) model
por: Xiong, Ao, et al.
Publicado: (2022)

HIF-1α Ameliorates Diabetic Neuropathic Pain via Parkin-Mediated Mitophagy in a Mouse Model
por: He, Jian, et al.
Publicado: (2022)

Astragaloside IV ameliorates diabetic nephropathy by modulating the mitochondrial quality control network
por: Liu, Xinhui, et al.
Publicado: (2017)

Alpha‐kinase1 promotes tubular injury and interstitial inflammation in diabetic nephropathy by canonical pyroptosis pathway
por: Cui, Xinyuan, et al.
Publicado: (2023)

Testosterone induces renal tubular epithelial cell death through the HIF-1α/BNIP3 pathway
por: Peng, Yonghan, et al.
Publicado: (2019)

Bilirubin Activates Transcription of HIF-1α in Human Proximal Tubular Cells Cultured in the Physiologic Oxygen Content
por: Kim, Sung Gyun, et al.
Publicado: (2014)

Formononetin Attenuates Renal Tubular Injury and Mitochondrial Damage in Diabetic Nephropathy Partly via Regulating Sirt1/PGC-1α Pathway
por: Huang, Qunwei, et al.
Publicado: (2022)

Corrigendum to “Probucol ameliorates renal injury in diabetic nephropathy by inhibiting the expression of the redox enzyme p66Shc” [Redox Biol. 13 (2017) 482–497]
por: Yang, Shikun, et al.
Publicado: (2019)

Correction to: Testosterone induces renal tubular epithelial cell death through the HIF-1α/BNIP3 pathway
por: Peng, Yonghan, et al.
Publicado: (2021)

DsbA-L interacting with catalase in peroxisome improves tubular oxidative damage in diabetic nephropathy
por: Liu, Yan, et al.
Publicado: (2023)

Riboflavin ameliorates mitochondrial dysfunction via the AMPK/PGC1α/HO‑1 signaling pathway and attenuates carbon tetrachloride‑induced liver fibrosis in rats
por: Tang, Ning, et al.
Publicado: (2022)

Ang-1 Gene Therapy Inhibits Hypoxia-Inducible Factor-1α (HIF-1α)-Prolyl-4-Hydroxylase-2, Stabilizes HIF-1α Expression, and Normalizes Immature Vasculature in db/db Mice
por: Chen, Jian-Xiong, et al.
Publicado: (2008)

Spleen Tyrosine Kinase Inhibition Ameliorates Tubular Inflammation in IgA Nephropathy
por: Yiu, Wai Han, et al.
Publicado: (2021)

Itaconate Suppresses Formation of Neutrophil Extracellular Traps (NETs): Involvement of Hypoxia-Inducible Factor 1α (Hif-1α) and Heme Oxygenase (HO-1)
por: Burczyk, Gabriela, et al.
Publicado: (2022)

Hypomethylation at non-CpG/CpG sites in the promoter of HIF-1α gene combined with enhanced H3K9Ac modification contribute to maintain higher HIF-1α expression in breast cancer
por: Li, Chun, et al.
Publicado: (2019)

HIF-1α-BNIP3-mediated mitophagy in tubular cells protects against renal ischemia/reperfusion injury
por: Fu, Zong-Jie, et al.
Publicado: (2020)

p66Shc: A novel biomarker of tubular oxidative injury in patients with diabetic nephropathy
por: Xu, Xiaoxuan, et al.
Publicado: (2016)

Endothelial Cell HIF-1α and HIF-2α Differentially Regulate Metastatic Success
por: Branco-Price, Cristina, et al.
Publicado: (2012)

MicroRNA-30c-5p ameliorates hypoxia-reoxygenation-induced tubular epithelial cell injury via HIF1α stabilization by targeting SOCS3
por: Zou, Yan-Fang, et al.
Publicado: (2017)

Trametenolic Acid Ameliorates the Progression of Diabetic Nephropathy in db/db Mice via Nrf2/HO-1 and NF-κB-Mediated Pathways
por: Duan, Qi, et al.
Publicado: (2022)

Tubular epithelial cell-derived extracellular vesicles induce macrophage glycolysis by stabilizing HIF-1α in diabetic kidney disease
por: Jia, Yijie, et al.
Publicado: (2022)

HIF-1α in cerebral ischemia
por: Dong, Peiliang, et al.
Publicado: (2022)

Sinapic Acid Ameliorates the Progression of Streptozotocin (STZ)-Induced Diabetic Nephropathy in Rats via NRF2/HO-1 Mediated Pathways
por: Alaofi, Ahmed L.
Publicado: (2020)

Drp1 activates ROS/HIF-1α/EZH2 and triggers mitochondrial fragmentation to deteriorate hypercalcemia-associated neuronal injury in mouse model of chronic kidney disease
por: Sun, Hongming, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_vipqn2nh730i5so6v3rbs2nbvn