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MiR‐22‐3p inhibits fibrotic cataract through inactivation of HDAC6 and increase of α‐tubulin acetylation

OBJECTIVES: Fibrotic cataract, including posterior capsule opacification (PCO) and anterior subcapsular cataract (ASC), renders millions of people visually impaired worldwide. However, the underlying mechanism remains poorly understood. Here, we report a miRNA‐based regulatory pathway that controls...

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Detalles Bibliográficos
Autores principales: Wang, Xiaoran, Wang, Liping, Sun, Yan, Chen, Baoxin, Xiong, Lang, Chen, Jieping, Huang, Mi, Wu, Jing, Tan, Xuhua, Zheng, Yingfeng, Huang, Shan, Liu, Yizhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7653254/
https://www.ncbi.nlm.nih.gov/pubmed/32985730
http://dx.doi.org/10.1111/cpr.12911