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PRKAR2B‐HIF‐1α loop promotes aerobic glycolysis and tumour growth in prostate cancer

OBJECTIVES: Reprogramming of cellular metabolism is profoundly implicated in tumorigenesis and can be exploited to cancer treatment. Cancer cells are known for their propensity to use glucose‐dependent glycolytic pathway instead of mitochondrial oxidative phosphorylation for energy generation even i...

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Detalles Bibliográficos
Autores principales: Xia, Lei, Sun, Jian, Xie, Shaowei, Chi, Chenfei, Zhu, Yinjie, Pan, Jiahua, Dong, Baijun, Huang, Yiran, Xia, Weiliang, Sha, Jianjun, Xue, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7653268/
https://www.ncbi.nlm.nih.gov/pubmed/33025691
http://dx.doi.org/10.1111/cpr.12918