Cargando…

PRKAR2B‐HIF‐1α loop promotes aerobic glycolysis and tumour growth in prostate cancer

OBJECTIVES: Reprogramming of cellular metabolism is profoundly implicated in tumorigenesis and can be exploited to cancer treatment. Cancer cells are known for their propensity to use glucose‐dependent glycolytic pathway instead of mitochondrial oxidative phosphorylation for energy generation even i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xia, Lei, Sun, Jian, Xie, Shaowei, Chi, Chenfei, Zhu, Yinjie, Pan, Jiahua, Dong, Baijun, Huang, Yiran, Xia, Weiliang, Sha, Jianjun, Xue, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7653268/ https://www.ncbi.nlm.nih.gov/pubmed/33025691 http://dx.doi.org/10.1111/cpr.12918

Ejemplares similares

PRKAR2B plays an oncogenic role in the castration-resistant prostate cancer
por: Sha, Jianjun, et al.
Publicado: (2016)

Efficacy of neoadjuvant docetaxel + cisplatin chemo-hormonal therapy versus docetaxel chemo-hormonal therapy in patients with locally advanced prostate cancer with germline DNA damage repair gene alterations
por: Chi, Chenfei, et al.
Publicado: (2022)

m(6)A-induced repression of SIAH1 facilitates alternative splicing of androgen receptor variant 7 by regulating CPSF1
por: Xia, Lei, et al.
Publicado: (2022)

Abiraterone acetate for chemotherapy-naive metastatic castration-resistant prostate cancer: a single-centre prospective study of efficacy, safety, and prognostic factors
por: Fan, Liancheng, et al.
Publicado: (2018)

Platelet to lymphocyte ratio as an independent prognostic indicator for prostate cancer patients receiving androgen deprivation therapy
por: Wang, Yanqing, et al.
Publicado: (2016)

The Microbiome of Prostate Fluid Is Associated With Prostate Cancer
por: Ma, Xiaowei, et al.
Publicado: (2019)

NPAS2 promotes aerobic glycolysis and tumor growth in prostate cancer through HIF-1A signaling
por: Ma, Shuaijun, et al.
Publicado: (2023)

Engineering the MoS(2)/MXene Heterostructure for Precise and Noninvasive Diagnosis of Prostate Cancer with Clinical Specimens
por: Xie, Shaowei, et al.
Publicado: (2023)

Transcriptomic signature defines two subtypes of locally advanced PCa with distinct neoadjuvant therapy benefits
por: Zhu, Yinjie, et al.
Publicado: (2023)

Serum Pre-Albumin Predicts the Clinical Outcome in Metastatic Castration-Resistant Prostate Cancer Patients Treated With Abiraterone
por: Fan, Liancheng, et al.
Publicado: (2017)

AB140. Efficacy of radical prostatectomy combined with neoadjuvant chemotherapy in the treatment of locally advanced prostate cancer: preliminary experiences from a single center
por: Xue, Wei, et al.
Publicado: (2016)

PRKAR1A and Thyroid Tumors
por: Pitsava, Georgia, et al.
Publicado: (2021)

PRKAR1A deficiency impedes hypertrophy and reduces heart size
por: Liu, Yuening, et al.
Publicado: (2020)

Targeting Aerobic Glycolysis and HIF-1α Expression Enhance Imiquimod-induced Apoptosis in Cancer Cells
por: Huang, Shi-Wei, et al.
Publicado: (2014)

MiR-186 inhibited aerobic glycolysis in gastric cancer via HIF-1α regulation
por: Liu, L, et al.
Publicado: (2016)

Klotho negatively regulated aerobic glycolysis in colorectal cancer via ERK/HIF1α axis
por: Li, Qingguo, et al.
Publicado: (2018)

MiR-186 inhibited aerobic glycolysis in gastric cancer via HIF-1α regulation
por: Liu, L, et al.
Publicado: (2017)

Tumour mitochondrial DNA mutations drive aerobic glycolysis to enhance checkpoint blockade
por: Mahmood, Mahnoor, et al.
Publicado: (2023)

Extended lymphadenectomy for high-risk prostate cancer in patients with chronic lymphocytic leukemia may not be necessary: a report of two cases
por: Zhu, Yinjie, et al.
Publicado: (2019)

Aerobic Glycolysis: Beyond Proliferation
por: Jones, William, et al.
Publicado: (2015)

EDDM3A drives gastric cancer progression by promoting HIF-1α-dependent aerobic glycolysis
por: Wu, Tao, et al.
Publicado: (2022)

SIPA1 Enhances Aerobic Glycolysis Through HIF-2α Pathway to Promote Breast Cancer Metastasis
por: Yao, Chenguang, et al.
Publicado: (2022)

Decreased TSPAN1 promotes prostate cancer progression and is a marker for early biochemical recurrence after radical prostatectomy
por: Xu, Fan, et al.
Publicado: (2016)

Albumin and Fibrinogen Combined Prognostic Grade Predicts Prognosis of Patients with Prostate Cancer
por: Wang, Yanqing, et al.
Publicado: (2017)

HO-1 Modulates Aerobic Glycolysis through LDH in Prostate Cancer Cells
por: Cascardo, Florencia, et al.
Publicado: (2021)

Novel Mutation in PRKAR1A in Carney Complex
por: Park, Ko Un, et al.
Publicado: (2012)

Hematopoietic neoplasms in Prkar2a-deficient mice
por: Saloustros, Emmanouil, et al.
Publicado: (2015)

α-Mangostin Alleviated HIF-1α-Mediated Angiogenesis in Rats With Adjuvant-Induced Arthritis by Suppressing Aerobic Glycolysis
por: Jiang, Tian-Tian, et al.
Publicado: (2021)

SENP1 Interacts with HIF1α to Regulate Glycolysis of Prostatic Carcinoma Cells
por: Wang, Chunyang, et al.
Publicado: (2019)

Role of aerobic glycolysis in genetically engineered mouse models of cancer
por: Dang, Chi V
Publicado: (2013)

Aerobic glycolysis, motility, and cytoskeletal remodeling
por: Verdone, James E, et al.
Publicado: (2015)

WWOX loss activates aerobic glycolysis
por: Abu-Remaileh, Muhannad, et al.
Publicado: (2014)

Proton export upregulates aerobic glycolysis
por: Russell, Shonagh, et al.
Publicado: (2022)

The HIF-1α antisense long non-coding RNA drives a positive feedback loop of HIF-1α mediated transactivation and glycolysis
por: Zheng, Fang, et al.
Publicado: (2021)

Artemisinin suppresses aerobic glycolysis in thyroid cancer cells by downregulating HIF-1a, which is increased by the XIST/miR-93/HIF-1a pathway
por: Yang, Fei, et al.
Publicado: (2023)

A novel AMPK activator shows therapeutic potential in hepatocellular carcinoma by suppressing HIF1α‐mediated aerobic glycolysis
por: Tseng, Hsing‐I, et al.
Publicado: (2022)

The ELAVL3/MYCN positive feedback loop provides a therapeutic target for neuroendocrine prostate cancer
por: Ji, Yiyi, et al.
Publicado: (2023)

CHD1 deletion stabilizes HIF1α to promote angiogenesis and glycolysis in prostate cancer
por: Wang, Yu-Zhao, et al.
Publicado: (2023)

LINC01605 promotes aerobic glycolysis through lactate dehydrogenase A in triple‐negative breast cancer
por: Wang, Wei, et al.
Publicado: (2022)

Oncogenic virus-induced aerobic glycolysis and tumorigenesis
por: Yu, Li, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_5ge1phdbrbet46beaal9hobvmj