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How quickly can we predict trimethoprim resistance using alchemical free energy methods?
The emergence of antimicrobial resistance threatens modern medicine and necessitates more personalized treatment of bacterial infections. Sequencing the whole genome of the pathogen(s) in a clinical sample offers one way to improve clinical microbiology diagnostic services, and has already been adop...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Royal Society
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7653339/ https://www.ncbi.nlm.nih.gov/pubmed/33178416 http://dx.doi.org/10.1098/rsfs.2019.0141 |