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Release from cell cycle arrest with Cdk4/6 inhibitors generates highly synchronized cell cycle progression in human cell culture

Each approach used to synchronize cell cycle progression of human cell lines presents a unique set of challenges. Induction synchrony with agents that transiently block progression through key cell cycle stages are popular, but change stoichiometries of cell cycle regulators, invoke compensatory cha...

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Detalles Bibliográficos
Autores principales: Trotter, Eleanor Wendy, Hagan, Iain Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7653349/
https://www.ncbi.nlm.nih.gov/pubmed/33052073
http://dx.doi.org/10.1098/rsob.200200