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Genomic profile of MYCN non-amplified neuroblastoma and potential for immunotherapeutic strategies in neuroblastoma

BACKGROUND: MYCN amplification is the most important genomic feature in neuroblastoma (NB). However, limited studies have been conducted on the MYCN non-amplified NB including low- and intermediate-risk NB. Here, the genomic characteristics of MYCN non-amplified NB were studied to allow for the iden...

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Detalles Bibliográficos
Autores principales: Lee, Eunjin, Lee, Ji Won, Lee, Boram, Park, Kyunghee, Shim, Joonho, Yoo, Keon Hee, Koo, Hong Hoe, Sung, Ki Woong, Park, Woong-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7653769/
https://www.ncbi.nlm.nih.gov/pubmed/33172452
http://dx.doi.org/10.1186/s12920-020-00819-5