Egr-1 mediates low-dose arecoline induced human oral mucosa fibroblast proliferation via transactivation of Wnt5a expression

BACKGROUND: Arecoline is an alkaloid natural product found in the areca nut that can induce oral submucous fibrosis and subsequent development of cancer. However, numerous studies have shown that arecoline may inhibit fibroblast proliferation and prevent collagen synthesis. RESULTS: High doses of ar...

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Detalles Bibliográficos
Autores principales: Chen, Qiang, Jiao, Jiuyang, Wang, Youyuan, Mai, Zhihui, Ren, Jing, He, Sijie, Li, Xiaolan, Chen, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7653895/
https://www.ncbi.nlm.nih.gov/pubmed/33167868
http://dx.doi.org/10.1186/s12860-020-00325-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7653895/
https://www.ncbi.nlm.nih.gov/pubmed/33167868
http://dx.doi.org/10.1186/s12860-020-00325-7

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