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CaMuS: simultaneous fitting and de novo imputation of cancer mutational signature

The identification of the mutational processes operating in tumour cells has implications for cancer diagnosis and therapy. These processes leave mutational patterns on the cancer genomes, which are referred to as mutational signatures. Recently, 81 mutational signatures have been inferred using com...

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Detalles Bibliográficos
Autores principales: Cartolano, Maria, Abedpour, Nima, Achter, Viktor, Yang, Tsun-Po, Ackermann, Sandra, Fischer, Matthias, Peifer, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7653908/
https://www.ncbi.nlm.nih.gov/pubmed/33168834
http://dx.doi.org/10.1038/s41598-020-75753-8