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Genetic analyses in mouse fibroblast and melanoma cells demonstrate novel roles for PDGF-AB ligand and PDGF receptor alpha

Platelet Derived Growth Factor Receptor (PDGFR) signaling is a central mitogenic pathway in development, as well as tissue repair and homeostasis. The rules governing the binding of PDGF ligand to the receptor to produce activation and downstream signaling have been well defined over the last severa...

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Detalles Bibliográficos
Autores principales: Kadrmas, Julie L., Beckerle, Mary C., Yoshigi, Masaaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7653911/
https://www.ncbi.nlm.nih.gov/pubmed/33168840
http://dx.doi.org/10.1038/s41598-020-75774-3