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Reconstitution of prospermatogonial specification in vitro from human induced pluripotent stem cells

Establishment of spermatogonia throughout the fetal and postnatal period is essential for production of spermatozoa and male fertility. Here, we establish a protocol for in vitro reconstitution of human prospermatogonial specification whereby human primordial germ cell (PGC)-like cells differentiate...

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Detalles Bibliográficos
Autores principales: Hwang, Young Sun, Suzuki, Shinnosuke, Seita, Yasunari, Ito, Jumpei, Sakata, Yuka, Aso, Hirofumi, Sato, Kei, Hermann, Brian P., Sasaki, Kotaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7653920/
https://www.ncbi.nlm.nih.gov/pubmed/33168808
http://dx.doi.org/10.1038/s41467-020-19350-3