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Reconstitution of prospermatogonial specification in vitro from human induced pluripotent stem cells
Establishment of spermatogonia throughout the fetal and postnatal period is essential for production of spermatozoa and male fertility. Here, we establish a protocol for in vitro reconstitution of human prospermatogonial specification whereby human primordial germ cell (PGC)-like cells differentiate...
Autores principales: | Hwang, Young Sun, Suzuki, Shinnosuke, Seita, Yasunari, Ito, Jumpei, Sakata, Yuka, Aso, Hirofumi, Sato, Kei, Hermann, Brian P., Sasaki, Kotaro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7653920/ https://www.ncbi.nlm.nih.gov/pubmed/33168808 http://dx.doi.org/10.1038/s41467-020-19350-3 |
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