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LncRNA NEAT1 remodels chromatin to promote the 5-Fu resistance by maintaining colorectal cancer stemness

Resistance of chemotherapy is one of causes of recurrence and poor prognosis in patients with colorectal cancer (CRC). The role of differentially expressed long non-coding RNA (lncRNA) in 5-fluorouracil (5-Fu) resistance has not been fully elucidated. Here we observed that lncRNA NEAT1 was associate...

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Detalles Bibliográficos
Autores principales: Zhu, Yihao, Hu, Hanqing, Yuan, Ziming, Zhang, Qian, Xiong, Huan, Hu, Zhiqiao, Wu, Hongyu, Huang, Rui, Wang, Guiyu, Tang, Qingchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7653927/
https://www.ncbi.nlm.nih.gov/pubmed/33168814
http://dx.doi.org/10.1038/s41419-020-03164-8