Cargando…

LncRNA NEAT1 remodels chromatin to promote the 5-Fu resistance by maintaining colorectal cancer stemness

Resistance of chemotherapy is one of causes of recurrence and poor prognosis in patients with colorectal cancer (CRC). The role of differentially expressed long non-coding RNA (lncRNA) in 5-fluorouracil (5-Fu) resistance has not been fully elucidated. Here we observed that lncRNA NEAT1 was associate...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhu, Yihao, Hu, Hanqing, Yuan, Ziming, Zhang, Qian, Xiong, Huan, Hu, Zhiqiao, Wu, Hongyu, Huang, Rui, Wang, Guiyu, Tang, Qingchao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7653927/ https://www.ncbi.nlm.nih.gov/pubmed/33168814 http://dx.doi.org/10.1038/s41419-020-03164-8

Ejemplares similares

Gut microbiota display alternative profiles in patients with early-onset colorectal cancer
por: Xiong, Huan, et al.
Publicado: (2022)

Natural Orifice Specimen Extraction Surgery versus Conventional Laparoscopic-Assisted Resection in the Treatment of Colorectal Cancer: A Propensity-Score Matching Study
por: Tang, Qingchao, et al.
Publicado: (2021)

Nomogram to Predict the Risk of Postoperative Anxiety and Depression in Colorectal Cancer Patients
por: Hu, Zhiqiao, et al.
Publicado: (2022)

Nomogram for predicting occurrence of synchronous liver metastasis in colorectal cancer: a single-center retrospective study based on pathological factors
por: Liu, Yunxiao, et al.
Publicado: (2022)

Loss of ABCB4 attenuates the caspase-dependent apoptosis regulating resistance to 5-Fu in colorectal cancer
por: Hu, Hanqing, et al.
Publicado: (2018)

Emerging roles for lncRNA-NEAT1 in colorectal cancer
por: Azizidoost, Shirin, et al.
Publicado: (2022)

LncRNA NEAT1 knockdown attenuates autophagy to elevate 5‐FU sensitivity in colorectal cancer via targeting miR‐34a
por: Liu, Fen, et al.
Publicado: (2019)

IgG Fc Binding Protein (FCGBP) is Down-Regulated in Metastatic Lesions and Predicts Survival in Metastatic Colorectal Cancer Patients
por: Yuan, Ziming, et al.
Publicado: (2021)

The lncRNA Neat1 promotes activation of inflammasomes in macrophages
por: Zhang, Pengfei, et al.
Publicado: (2019)

LncRNA NEAT1 Regulates 5-Fu Sensitivity, Apoptosis and Invasion in Colorectal Cancer Through the MiR-150-5p/CPSF4 Axis
por: Wang, Xuesong, et al.
Publicado: (2020)

The Diagnostic and Prognostic Value of Serum lncRNA NEAT1 in Colorectal Cancer
por: Wang, Yong, et al.
Publicado: (2020)

lncRNA NEAT1 Promotes Colorectal Cancer Progression by Increasing Inflammation
por: Chen, Qingmin, et al.
Publicado: (2022)

Nomogram to Predict the Occurrence and Prognosis of Distant Metastasis in T1N0 Colon Cancer: A SEER Data-Based Study
por: Liu, Yunxiao, et al.
Publicado: (2021)

LncRNA GAS8‐AS1 downregulates lncRNA NEAT1 to inhibit glioblastoma cell proliferation
por: Wu, Xiaoming, et al.
Publicado: (2021)

Long non-coding RNA H19 confers 5-Fu resistance in colorectal cancer by promoting SIRT1-mediated autophagy
por: Wang, Meng, et al.
Publicado: (2018)

Inhibition of lncRNA-NEAT1 sensitizes 5-Fu resistant cervical cancer cells through de-repressing the microRNA-34a/LDHA axis
por: Shao, Xuecheng, et al.
Publicado: (2021)

The Expression of lncRNA NEAT1 in Human Tuberculosis and Its Antituberculosis Effect
por: Huang, Shuying, et al.
Publicado: (2018)

Expression and Clinical Significance of lncRNA NEAT1 in Patients with Spinal Tuberculosis
por: Zheng, Jianping, et al.
Publicado: (2022)

lncRNA transcription induces meiotic recombination through chromatin remodelling in fission yeast
por: Senmatsu, Satoshi, et al.
Publicado: (2021)

LncRNA NEAT1 Recruits SFPQ to Regulate MITF Splicing and Control RPE Cell Proliferation
por: Hu, Xiaojuan, et al.
Publicado: (2021)

Interplay of lncRNA H19/miR‐675 and lncRNA NEAT1/miR‐204 in breast cancer
por: Müller, Volkmar, et al.
Publicado: (2019)

Integrator restrains paraspeckles assembly by promoting isoform switching of the lncRNA NEAT1
por: Barra, Jasmine, et al.
Publicado: (2020)

LncRNA NEAT1 facilitates glioma progression via stabilizing PGK1
por: Liang, Jingshan, et al.
Publicado: (2022)

Targeted Methylation of the LncRNA NEAT1 Suppresses Malignancy of Renal Cell Carcinoma
por: Chen, Jieqing, et al.
Publicado: (2021)

LncRNA NEAT1 mediates intestinal inflammation by regulating TNFRSF1B
por: Pan, Shiyu, et al.
Publicado: (2021)

Downregulation of lncRNA NEAT1 alleviates sepsis-induced acute kidney injury
por: Zhou, Yuhua, et al.
Publicado: (2022)

Dyslipidemia initiates keratinocytes proliferation through upregulation of lncRNA NEAT in psoriasis patients
por: Mostafa, Abeer, et al.
Publicado: (2023)

lncRNA NEAT1 promotes the proliferation and metastasis of hepatocellular carcinoma by regulating the FOXP3/PKM2 axis
por: Pan, Junping, et al.
Publicado: (2022)

Colorectal cancer cell intrinsic fibroblast activation protein alpha binds to Enolase1 and activates NF-κB pathway to promote metastasis
por: Yuan, Ziming, et al.
Publicado: (2021)

HuR‐regulated lncRNA NEAT1 stability in tumorigenesis and progression of ovarian cancer
por: Chai, Yiqing, et al.
Publicado: (2016)

Diagnostic Value of the lncRNA NEAT1 in Peripheral Blood Mononuclear Cells of Patients with Sepsis
por: Huang, Shuying, et al.
Publicado: (2017)

LncRNA NEAT1 is upregulated in recurrent aphthous stomatitis (RAS) and has predictive values
por: Han, Yaolun, et al.
Publicado: (2021)

LncRNA ontology: inferring lncRNA functions based on chromatin states and expression patterns
por: Li, Yongsheng, et al.
Publicado: (2015)

Knockdown of the oncogene lncRNA NEAT1 restores the availability of miR-34c and improves the sensitivity to cisplatin in osteosarcoma
por: Hu, Yuliang, et al.
Publicado: (2018)

Long Noncoding RNA JAKMIP2-AS1 Promotes the Growth of Colorectal Cancer and Indicates Poor Prognosis
por: Ma, Tianyi, et al.
Publicado: (2021)

LncRNA NEAT1 promotes the tumorigenesis of colorectal cancer by sponging miR‐193a‐3p
por: Yu, Hong‐Mei, et al.
Publicado: (2018)

The lncRNA Neat1 is required for corpus luteum formation and the establishment of pregnancy in a subpopulation of mice
por: Nakagawa, Shinichi, et al.
Publicado: (2014)

The oestrogen receptor alpha-regulated lncRNA NEAT1 is a critical modulator of prostate cancer
por: Chakravarty, Dimple, et al.
Publicado: (2014)

ALKBH5 promotes invasion and metastasis of gastric cancer by decreasing methylation of the lncRNA NEAT1
por: Zhang, Jun, et al.
Publicado: (2019)

LncRNA NEAT1 in Paraspeckles: A Structural Scaffold for Cellular DNA Damage Response Systems?
por: Taiana, Elisa, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_mqgr5dv5v5qarnu1hko28auikt