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CRISPR/Cas9 as an antiviral against Orthopoxviruses using an AAV vector

A vaccine for smallpox is no longer administered to the general public, and there is no proven, safe treatment specific to poxvirus infections, leaving people susceptible to infections by smallpox and other zoonotic Orthopoxviruses such as monkeypox. Using vaccinia virus (VACV) as a model organism f...

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Detalles Bibliográficos
Autores principales: Siegrist, Cathryn M., Kinahan, Sean M., Settecerri, Taylor, Greene, Adrienne C., Santarpia, Joshua L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7653928/
https://www.ncbi.nlm.nih.gov/pubmed/33168908
http://dx.doi.org/10.1038/s41598-020-76449-9