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Evidence for hypoxia increasing the tempo of evolution in glioblastoma

BACKGROUND: Tumour hypoxia is associated with metastatic disease, and while there have been many mechanisms proposed for why tumour hypoxia is associated with metastatic disease, it remains unclear whether one precise mechanism is the key reason or several in concert. Somatic evolution drives cancer...

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Detalles Bibliográficos
Autores principales: Grimes, David Robert, Jansen, Marnix, Macauley, Robert J., Scott, Jacob G., Basanta, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7653934/
https://www.ncbi.nlm.nih.gov/pubmed/32848201
http://dx.doi.org/10.1038/s41416-020-1021-5