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Evidence for hypoxia increasing the tempo of evolution in glioblastoma
BACKGROUND: Tumour hypoxia is associated with metastatic disease, and while there have been many mechanisms proposed for why tumour hypoxia is associated with metastatic disease, it remains unclear whether one precise mechanism is the key reason or several in concert. Somatic evolution drives cancer...
Autores principales: | Grimes, David Robert, Jansen, Marnix, Macauley, Robert J., Scott, Jacob G., Basanta, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7653934/ https://www.ncbi.nlm.nih.gov/pubmed/32848201 http://dx.doi.org/10.1038/s41416-020-1021-5 |
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