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Risk Stratification for Bipolar Disorder Using Polygenic Risk Scores Among Young High-Risk Adults

Objective: Identifying high-risk groups with an increased genetic liability for bipolar disorder (BD) will provide insights into the etiology of BD and contribute to early detection of BD. We used the BD polygenic risk score (PRS) derived from BD genome-wide association studies (GWAS) to explore how...

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Detalles Bibliográficos
Autores principales: Biere, Silvia, Kranz, Thorsten M., Matura, Silke, Petrova, Kristiyana, Streit, Fabian, Chiocchetti, Andreas G., Grimm, Oliver, Brum, Murielle, Brunkhorst-Kanaan, Natalie, Oertel, Viola, Malyshau, Aliaksandr, Pfennig, Andrea, Bauer, Michael, Schulze, Thomas G., Kittel-Schneider, Sarah, Reif, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7653940/
https://www.ncbi.nlm.nih.gov/pubmed/33192665
http://dx.doi.org/10.3389/fpsyt.2020.552532