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Mitochondrial hyperactivity as a potential therapeutic target in Parkinson’s disease

Mitochondrial dysfunction is thought to contribute to neurodegeneration in Parkinson’s disease (PD), yet the cellular events that lead to mitochondrial disruption remain unclear. Post-mortem studies of PD patient brains and the use of complex I inhibitors to model the disease previously suggested a...

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Detalles Bibliográficos
Autores principales: Mor, Danielle E., Murphy, Coleen T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7653964/
https://www.ncbi.nlm.nih.gov/pubmed/33178902
http://dx.doi.org/10.1016/j.tma.2020.07.007