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Single-cell transcriptome conservation in a comparative analysis of fresh and cryopreserved human skin tissue: pilot in localized scleroderma

BACKGROUND: The purpose of this study was to assess variability in cell composition and cell-specific gene expression in the skin of patients with localized scleroderma (LS) utilizing CryoStor® CS10 in comparison to RPMI to produce adequate preservation of tissue samples and cell types of interest f...

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Detalles Bibliográficos
Autores principales: Mirizio, Emily, Tabib, Tracy, Wang, Xiao, Chen, Wei, Liu, Christopher, Lafyatis, Robert, Jacobe, Heidi, Torok, Kathryn S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7654179/
https://www.ncbi.nlm.nih.gov/pubmed/33168063
http://dx.doi.org/10.1186/s13075-020-02343-4