Protrudin-deficient mice manifest depression-like behavior with abnormalities in activity, attention, and cued fear-conditioning

Protrudin is a protein that resides in the membrane of the endoplasmic reticulum and is highly expressed in the nervous system. Although mutations in the human protrudin gene (ZFYVE27, also known as SPG33) give rise to hereditary spastic paraplegia (HSP), the physiological role of the encoded protei...

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Detalles Bibliográficos
Autores principales: Shirane, Michiko, Shoji, Hirotaka, Hashimoto, Yutaka, Katagiri, Hiroyuki, Kobayashi, Shizuka, Manabe, Toshiya, Miyakawa, Tsuyoshi, Nakayama, Keiichi I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7654181/
https://www.ncbi.nlm.nih.gov/pubmed/33172474
http://dx.doi.org/10.1186/s13041-020-00693-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7654181/
https://www.ncbi.nlm.nih.gov/pubmed/33172474
http://dx.doi.org/10.1186/s13041-020-00693-3

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