Cargando…
Discovery of Benzyl Tetraphosphonate Derivative as Inhibitor of Human Factor Xia
The inhibition of factor XIa (FXIa) is a trending paradigm for the development of new generations of anticoagulants without a substantial risk of bleeding. In this report, we present the discovery of a benzyl tetra‐phosphonate derivative as a potent and selective inhibitor of human FXIa. Biochemical...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7654249/ https://www.ncbi.nlm.nih.gov/pubmed/33204588 http://dx.doi.org/10.1002/open.202000277 |