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From angiotensin-converting enzyme 2 disruption to thromboinflammatory microvascular disease: A paradigm drawn from COVID-19

We concisely review clinical, autopsy, experimental and molecular data of 2019 coronavirus disease (COVID-19). Angiotensin-converting enzyme 2 disruption and thromboinflammatory microangiopathy emerge as distinctive features. Briefly, entry of the virus into microvessels can profoundly disrupt the l...

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Detalles Bibliográficos
Autores principales: Vinci, R., Pedicino, D., Andreotti, F., Russo, G., D'Aiello, A., De Cristofaro, R., Crea, F., Liuzzo, G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7654294/
https://www.ncbi.nlm.nih.gov/pubmed/33181158
http://dx.doi.org/10.1016/j.ijcard.2020.11.016