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Light control of RTK activity: from technology development to translational research

Inhibition of receptor tyrosine kinases (RTKs) by small molecule inhibitors and monoclonal antibodies is used to treat cancer. Conversely, activation of RTKs with their ligands, including growth factors and insulin, is used to treat diabetes and neurodegeneration. However, conventional therapies tha...

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Detalles Bibliográficos
Autores principales: Leopold, Anna V., Verkhusha, Vladislav V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7654314/
https://www.ncbi.nlm.nih.gov/pubmed/33209247
http://dx.doi.org/10.1039/d0sc03570j