Cargando…
Light control of RTK activity: from technology development to translational research
Inhibition of receptor tyrosine kinases (RTKs) by small molecule inhibitors and monoclonal antibodies is used to treat cancer. Conversely, activation of RTKs with their ligands, including growth factors and insulin, is used to treat diabetes and neurodegeneration. However, conventional therapies tha...
Autores principales: | Leopold, Anna V., Verkhusha, Vladislav V. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7654314/ https://www.ncbi.nlm.nih.gov/pubmed/33209247 http://dx.doi.org/10.1039/d0sc03570j |
Ejemplares similares
-
Neurotrophin receptor tyrosine kinases regulated with near-infrared light
por: Leopold, Anna V., et al.
Publicado: (2019) -
An optogenetic system based on bacterial phytochrome controllable with near-infrared light
por: Kaberniuk, Andrii A., et al.
Publicado: (2016) -
The trigger (and the restriction) of Torso RTK activation
por: Mineo, Alessandro, et al.
Publicado: (2018) -
Fluorescent Biosensors for Neurotransmission and Neuromodulation: Engineering and Applications
por: Leopold, Anna V., et al.
Publicado: (2019) -
Conserved and divergent elements in Torso RTK activation in Drosophila development
por: Grillo, Marco, et al.
Publicado: (2012)