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SLy2‐deficiency promotes B‐1 cell immunity and triggers enhanced production of IgM and IgG(2) antibodies against pneumococcal vaccine

BACKGROUND: Despite the benefits of existing vaccines, Streptococcus pneumoniae is still responsible for the greatest proportion of respiratory tract infections around the globe, thereby substantially contributing to morbidity and mortality in humans. B‐1 cells are key players of bacterial clearance...

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Detalles Bibliográficos
Autores principales: Jaufmann, Jennifer, Tümen, Leyla, Schmitt, Fee, Schäll, Daniel, von Holleben, Max, Beer‐Hammer, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7654406/
https://www.ncbi.nlm.nih.gov/pubmed/33098380
http://dx.doi.org/10.1002/iid3.365