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A role for the Sts phosphatases in negatively regulating IFNγ‐mediated production of nitric oxide in monocytes

INTRODUCTION: The atypical Sts phosphatases negatively regulate signaling pathways in diverse immune cell types, with two of their molecular targets being the related kinases Syk and Zap‐70. Mice lacking Sts expression (Sts (−/−)) are resistant to infection by the live vaccine strain (LVS) of Franci...

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Detalles Bibliográficos
Autores principales: Parashar, Kaustubh, Carpino, Nicholas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7654413/
https://www.ncbi.nlm.nih.gov/pubmed/32841534
http://dx.doi.org/10.1002/iid3.336